Search on: AMYLOID BETA-PROTEIN PRECURSOR 
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Descriptor English:   Amyloid beta-Protein Precursor 
Descriptor Spanish:   Precursor de Proteína beta-Amiloide 
Descriptor Portuguese:   Precursor de Proteína beta-Amiloide 
Synonyms English:   Amyloid beta Precursor Protein
Protease Nexin 2
Protease Nexin II
Amyloid beta Protein Precursor
Nexin 2, Protease
Nexin II, Protease
beta Amyloid Protein Precursor
beta-Protein Precursor, Amyloid
beta-Amyloid Protein Precursor
Amyloid Protein Precursor
Amyloid A4 Protein Precursor  
Tree Number:   D12.776.049.407.249
D12.776.543.039
D12.776.645.468.500
D12.776.811.050
Definition English:   A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES. 
History Note English:   92; was AMYLOID BETA PROTEIN PRECURSOR (NM) 1988-91; AMYLOID A4 PROTEIN PRECURSOR was NM 1987-94 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30268 
Unique Identifier:   D016564 

Occurrence in VHL:
 

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